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Much progress has been made in the last 5 years in the development of new drugs for the treatment of type 2 diabetes. Below is a chart of the “diabetes pills” currently on the market. Remember to always take your medications as prescribed by your physician. Never make a change in your medications without first consulting with your physician.

Class Name of Med Action Possible Side Effects
SULFONYLUREAS

Glucotrol, Glucotrol XL (glipizide)
Diabeta, Micronase, Glynase (glyburide),
Amaryl (glimepiride)


Helps your body (your pancreas) send out more of its own insulin. Gastrointestinal problems, low blood sugar reaction, alcohol intolerance, skin reaction, sun sensitivity, weight gain, allergy to sulfa
BIGUANIDES Glucophage (metformin)
Glucophage XR
Fortamet
Riomet (liquid form)

Decreases the liver’s glucose production; enhances the absorption of glucose in other parts of the body.


Nausea, bloating, cramping, diarrhea, loss of appetite
(Minimize side effects by taking with food)
May interact with IV contrast dye used with medical testing
Caution with alcohol intake
ALPHA-GLUCOSIDASE INHIBITORS Precose (acarbose)
Glyset (miglitol)

Decreases the liver’s glucose production; enhances the absorption of glucose in other parts of the body.


Nausea, bloating, cramping, diarrhea, loss of appetite
(Minimize side effects by taking with food)
May interact with IV contrast dye used with medical testing
Caution with alcohol intake
THIAZOLIDINEDIONES Actos (pioglitazone)
Avandia (rosiglitazone)
Helps the body to use insulin more effectively, especially in the muscle cells.

Upper respiratory tract infections, headache, sinus infection, sore throat, muscle pain, tooth disorders, dizziness, swelling

 

MEGLITINIDES Prandin (repaglinide)
Starlix (nareglinide)
Helps your body (your pancreas) send out more of its own insulin. These work very quickly and are meant to be taken just before meals.

Low blood sugar reaction, headache, nausea, upper respiratory tract infection, back pain, joint pain, weight gain, nasal and sinus inflammation

 

 

 
 
© 2007 Diabetes Care & Education, Inc.